29 Categories
Category Clones KO
In Clones %(Clones/Pathways) In Pathways
Translation 134 66 36.46% 181
Nervous System 67 23 35.94% 64
Neurodegenerative Disorders 60 30 32.97% 91
Metabolism of Other Amino Acids 84 35 30.70% 114
Endocrine System 113 46 30.26% 152
Lipid Metabolism 216 80 28.78% 278
Cell Communication 164 68 27.76% 245
Replication and Repair 21 14 25.00% 56
Nucleotide Metabolism 73 39 24.84% 157
Sensory System 26 9 24.32% 37
Biosynthesis of Secondary Metabolites 47 28 24.14% 116
"Folding, Sorting and Degradation" 126 69 23.47% 294
Amino Acid Metabolism 302 116 23.02% 504
Infectious Diseases 20 12 21.82% 55
Transcription 31 21 21.21% 99
Signal Transduction 224 101 19.96% 506
Development 29 20 19.05% 105
Carbohydrate Metabolism 248 95 17.12% 555
Energy Metabolism 146 89 16.89% 527
Cell Motility 56 34 16.50% 206
Cell Growth and Death 13 10 16.39% 61
Metabolism of Cofactors and Vitamins 79 51 16.14% 316
Immune System 109 56 16.00% 350
Glycan Biosynthesis and Metabolism 136 37 15.95% 232
Xenobiotics Biodegradation and Metabolism 112 32 15.61% 205
Membrane Transport 52 31 12.20% 254
Metabolic Disorders 14 8 11.76% 68
Signaling Molecules and Interaction 119 80 11.44% 699
Biosynthesis of Polyketides and Nonribosomal Peptides 5 2 4.76% 42
Total 2826 856 17.36% 4931



182 (out of 196) pathways

Pathway: Ribosome ( 94, 48, 32.7%, 147 )
Query Def Hit ID Hit Def Bit Score E-Value Kegg Ortholog Other Pathways
APL_all_052305.210.C1 hsa:6189 RPS3A; ribosomal protein S3A [KO:K02984] 407 0.0 K02984  
APL_all_052305.21.C14 rno:64306 Rpl27; ribosomal protein L27 [KO:K02901] 219 0.0 K02901  
PEG001-C-008848-301 hsa:6137 RPL13; ribosomal protein L13 [KO:K02873] 62 1.47908E-8 K02873  
APL_all_052305.2409.C2 dre:406387 rpl26; ribosomal protein L26 [KO:K02898] 196 0.0 K02898  
APL_all_052305.22.C2 bta:493714 RPL15; ribosomal protein L15 [KO:K02877] 342 0.0 K02877  
APL_all_052305.1094.C1 dre:406266 c15orf15; chromosome 15 open reading frame 15 (H. sapiens) [KO:K02896] 233 0.0 K02896  
PEG001-C-002057-501 dme:CG7283-PA CG7283; CG7283 gene product from transcript CG7283-RA [KO:K02865] 224 0.0 K02865  
MCCN20-F-111678-501 xla:444362 MGC82841; MGC82841 protein [KO:K02962] 37 0.0896658 K02962  
APL_all_052305.22.C1 bta:493714 RPL15; ribosomal protein L15 [KO:K02877] 342 0.0 K02877  
MCCN25-F-014039-501 rno:161477 Rps13; ribosomal protein S13 [KO:K02953] 51 2.0278E-5 K02953  
APL_all_052305.5716.C2 cel:Y37E3.7 rpa-1; Ribosomal protein, acidic protein 1 [KO:K02942] 100 2.14651E-20 K02942  
APL_all_052305.1558.C1 xtr:448693 MGC89973; MGC89973 protein [KO:K02949] 253 0.0 K02949  
APL_all_052305.114.C2 xla:446306 rpl13-prov; ribosomal protein L13 [KO:K02873] 203 0.0 K02873  
APL_all_052305.1082.C1 xtr:448703 MGC89670; MGC89670 protein [KO:K02976] 144 1.03345E-33 K02976  
APL_all_052305.177.C3 xtr:496439 rpl18; ribosomal protein L18 [KO:K02883] 226 0.0 K02883  
AXOP26-F-036552-501 vpa:VP0279 ribosomal protein S13 [KO:K02952] 223 0.0 K02952  
APL_all_052305.250.C2 xtr:493270 TTpA018i12.1, MGC89830; ribosomal protein S12 [KO:K02951] 186 0.0 K02951  
MCC013-F-016728-501 xtr:394724 MGC75699; ribosomal protein S3 [KO:K02985] 189 0.0 K02985  
CNSN01-C-007481-501 xtr:448689 MGC89958; MGC89958 protein [KO:K02893] 64 6.21672E-9 K02893  
APL_all_052305.5656.C2 dme:CG8495-PA Dmel_CG8495; CG8495 gene product from transcript CG8495-RA [KO:K02980] 83 5.83993E-17 K02980  
CNSN01-F-149369-501 dre:406266 c15orf15; chromosome 15 open reading frame 15 (H. sapiens) [KO:K02896] 175 1.29E-42 K02896  
CNSN01-F-152264-501 xtr:496439 rpl18; ribosomal protein L18 [KO:K02883] 264 0.0 K02883  
APL_all_052305.5716.C1 cel:Y37E3.7 rpa-1; Ribosomal protein, acidic protein 1 [KO:K02942] 107 1.57247E-22 K02942  
APL_all_052305.1.C1754 rno:161477 Rps13; ribosomal protein S13 [KO:K02953] 53 2.44047E-6 K02953  
APL_all_052305.913.C1 dre:406485 zgc:77758 [KO:K02969] 200 0.0 K02969  
PEG001-C-001687-301 dre:393788 rps25; ribosomal protein S25 [KO:K02975] 48 8.24285E-7 K02975  
MCCN24-F-014474-501 rno:29304 Rps6; ribosomal protein S6 [KO:K02991] 230 0.0 K02991
  • mTOR signaling pathway
  • Insulin signaling pathway
    • APL_all_052305.154.C3 rno:83789 Rps2; ribosomal protein S2 [KO:K02981] 232 0.0 K02981  
    PEG001-C-004537-501 xla:446456 MGC78885; MGC78885 protein [KO:K02880] 249 0.0 K02880  
    APL_all_052305.7008.C1 dre:336726 zgc:77235 [KO:K02900] 181 4.2E-45 K02900  
    CNSN01-F-146721-501 dre:394027 rpsa; ribosomal protein SA [KO:K02998] 135 1.10994E-30 K02998
  • Prion disease
    • APL_all_052305.424.C2 dme:CG8922-PA CG8922; CG8922 gene product from transcript CG8922-RA [KO:K02989] 160 4.23773E-39 K02989  
    AXOP26-F-036551-501 xtr:496894 LOC496894; hypothetical LOC496894 [KO:K02912] 117 9.25116E-30 K02912  
    CNSN01-F-106358-501 ssc:414422 RPL11; 60S ribosomal protein L11 [KO:K02868] 243 0.0 K02868  
    CNSN01-F-049323-501 xla:414688 MGC83076; hypothetical protein MGC83076 [KO:K02875] 110 1.31154E-24 K02875  
    APL_all_052305.1179.C3 ssc:397607 RPS15; rig-analog DNA-binding protein [KO:K02958] 166 2.9843E-40 K02958  
    APL_all_052305.839.C2 xtr:496894 LOC496894; hypothetical LOC496894 [KO:K02912] 196 0.0 K02912  
    APL_all_052305.1.C342 rno:161477 Rps13; ribosomal protein S13 [KO:K02953] 256 0.0 K02953  
    CNSN01-F-082961-501 rno:81775 Rps21; ribosomal protein S21 [KO:K02971] 71 4.74849E-11 K02971  
    CNSN01-F-068966-501 xtr:448704 MGC89675; MGC89675 protein [KO:K02885] 104 2.3841E-21 K02885  
    PEG003-C-207706-501 hsa:6188 RPS3; ribosomal protein S3 [KO:K02985] 314 0.0 K02985  
    APL_all_052305.854.C2 rno:81773 Rps10; ribosomal protein S10 [KO:K02947] 38 0.0477241 K02947  
    APL_all_052305.81.C1 rno:300079 Rpl3; ribosomal protein L3 [KO:K02925] 365 0.0 K02925  
    APL_all_052305.1.C298 xtr:448717 TNeu023b09.1, MGC89840; ribosomal protein L35 [KO:K02917] 169 1.5501E-41 K02917  
    CNSN01-C-002620-501 dme:CG11276-PA CG11276; CG11276 gene product from transcript CG11276-RA CG11276 gene product from transcript CG11276-RB [KO:K02987] 242 0.0 K02987  
    APL_all_052305.1.CB234 cel:F28D1.7 rps-23; Hypothetical protein F28D1.7 [KO:K02973] 238 0.0 K02973  
    APL_all_052305.197.C2 ssc:396980 RPS18; ribosomal protein S18 [KO:K02964] 231 0.0 K02964  
    APL_all_052305.1179.C4 ssc:397607 RPS15; rig-analog DNA-binding protein [KO:K02958] 155 4.49193E-37 K02958  
    APL_all_052305.4.C1 xtr:394665 TNeu119p20.1, MGC75768; ribosomal protein SA [KO:K02998] 331 0.0 K02998
  • Prion disease
    • PEG001-C-001539-501 rno:300079 Rpl3; ribosomal protein L3 [KO:K02925] 213 0.0 K02925  
    CNSN27-F-039754-501 cpv:cgd5_2780 40S ribosomal protein S10, transcript identified by EST [KO:K02947] 35 0.823313 K02947  
    PEG001-C-004496-301 xtr:496609 TNeu055f11.1, LOC496609; ribosomal protein S15 [KO:K02958] 44 0.00478527 K02958  
    LAR021-F-012846-501 ath:At5g39850 K13H13.2; 40S ribosomal protein S9 (RPS9C) [KO:K02997] 165 6.01081E-40 K02997  
    APL_all_052305.114.C1 dre:378961 rpl13; ribosomal protein L13 [KO:K02873] 244 0.0 K02873  
    APL_all_052305.197.C1 ssc:396980 RPS18; ribosomal protein S18 [KO:K02964] 151 1.4E-45 K02964  
    APL_all_052305.1082.C2 xtr:448703 MGC89670; MGC89670 protein [KO:K02976] 149 2.15426E-35 K02976  
    APL_all_052305.1558.C2 xtr:448693 MGC89973; MGC89973 protein [KO:K02949] 238 0.0 K02949  
    APL_all_052305.177.C4 xtr:496439 rpl18; ribosomal protein L18 [KO:K02883] 293 0.0 K02883  
    APL_all_052305.1082.C3 hsa:441486 LOC441486; similar to 40S ribosomal protein S26 [KO:K02976] 122 3.50348E-27 K02976  
    APL_all_052305.21.C3 rno:64306 Rpl27; ribosomal protein L27 [KO:K02901] 208 0.0 K02901  
    CNS003-F-026291-501 mge:MG176 rpsK, rpS11; 30S ribosomal protein S11 [KO:K02948] 36 0.753119 K02948  
    PEG003-C-221259-501 spo:SPCC1259.01c-2 rps18-2; ribosomal protein subunit s18 [KO:K02964] 37 0.88708 K02964  
    APL_all_052305.91.C1 xtr:394724 MGC75699; ribosomal protein S3 [KO:K02985] 419 0.0 K02985  
    PEG001-C-002053-301 dme:CG10944-PC CG10944; CG10944 gene product from transcript CG10944-RC [KO:K02991] 167 0.0 K02991
  • mTOR signaling pathway
  • Insulin signaling pathway
    • APL_all_052305.5656.C1 dme:CG8495-PA Dmel_CG8495; CG8495 gene product from transcript CG8495-RA [KO:K02980] 108 2.02278E-23 K02980  
    PEG001-C-009449-501 rno:300079 Rpl3; ribosomal protein L3 [KO:K02925] 350 0.0 K02925  
    APL_all_052305.169.CB1 xla:414368 rpS8B; ribosomal protein S8 (rpS8B) [KO:K02993] 309 0.0 K02993  
    PEG002-C-008462-501 rno:317646 Rpl13a; ribosomal protein L13A [KO:K02872] 244 0.0 K02872  
    PEG003-C-206984-501 hsa:6189 RPS3A; ribosomal protein S3A [KO:K02984] 207 0.0 K02984  
    APL_all_052305.881.C1 xla:446456 MGC78885; MGC78885 protein [KO:K02880] 259 0.0 K02880  
    APL_all_052305.91.C3 hsa:6188 RPS3; ribosomal protein S3 [KO:K02985] 357 0.0 K02985  
    APL_all_052305.2880.C1 xla:414688 MGC83076; hypothetical protein MGC83076 [KO:K02875] 89 2.97756E-33 K02875  
    APL_all_052305.82.C4 xtr:394521 MGC75725; 60S ribosomal protein L8 [KO:K02938] 444 0.0 K02938  
    APL_all_052305.22.C3 bta:493714 RPL15; ribosomal protein L15 [KO:K02877] 188 0.0 K02877  
    APL_all_052305.36.C2 dme:CG11276-PA CG11276; CG11276 gene product from transcript CG11276-RA CG11276 gene product from transcript CG11276-RB [KO:K02987] 397 0.0 K02987  
    CNSN27-F-041253-501 xla:446456 MGC78885; MGC78885 protein [KO:K02880] 257 0.0 K02880  
    CNSN01-F-141303-501 dme:CG6141-PA CG6141; CG6141 gene product from transcript CG6141-RA CG6141 gene product from transcript CG6141-RB [KO:K02940] 83 2.73124E-20 K02940  
    PEG003-C-211883-501 spo:SPBC18H10.12c rpl7c; 60s ribosomal protein l7-c. [KO:K02937] 50 8.22541E-5 K02937  
    APL_all_052305.20.C8 xla:380386 rps27-prov; ribosomal protein S27 [KO:K02978] 145 1.142E-33 K02978  
    APL_all_052305.16.C1 dme:CG2746-PA CG2746; CG2746 gene product from transcript CG2746-RA CG2746 gene product from transcript CG2746-RB [KO:K02885] 236 0.0 K02885  
    APL_all_052305.1179.C1 ssc:397607 RPS15; rig-analog DNA-binding protein [KO:K02958] 157 1.6121E-37 K02958  
    APL_all_052305.1.C336 cel:F28D1.7 rps-23; Hypothetical protein F28D1.7 [KO:K02973] 266 0.0 K02973  
    APL_all_052305.91.C4 hsa:6188 RPS3; ribosomal protein S3 [KO:K02985] 403 0.0 K02985  
    APL_all_052305.154.C1 rno:83789 Rps2; ribosomal protein S2 [KO:K02981] 384 0.0 K02981  
    CNSN01-F-096177-501 spo:SPAC959.08 rpl21-2; 60s ribosomal protein l21 [KO:K02889] 95 8.64982E-33 K02889  
    APL_all_052305.1.C236 ath:At3g09630 F11F8.22; 60S ribosomal protein L4/L1 (RPL4A) [KO:K02930] 94 3.13126E-18 K02930  
    APL_all_052305.2880.C2 xla:414688 MGC83076; hypothetical protein MGC83076 [KO:K02875] 158 7.61028E-38 K02875  
    APL_all_052305.36.C1 dme:CG11276-PA CG11276; CG11276 gene product from transcript CG11276-RA CG11276 gene product from transcript CG11276-RB [KO:K02987] 334 0.0 K02987  
    APL_all_052305.197.C3 ssc:396980 RPS18; ribosomal protein S18 [KO:K02964] 147 0.0 K02964  
    APL_all_052305.210.C2 hsa:6189 RPS3A; ribosomal protein S3A [KO:K02984] 298 0.0 K02984  
    APL_all_052305.839.C1 xtr:496894 LOC496894; hypothetical LOC496894 [KO:K02912] 195 0.0 K02912  
    APL_all_052305.177.C1 xtr:496439 rpl18; ribosomal protein L18 [KO:K02883] 221 0.0 K02883  
    APL_all_052305.177.C2 xtr:496439 rpl18; ribosomal protein L18 [KO:K02883] 300 0.0 K02883  
    APL_all_052305.228.CB1 xla:379816 rps9-prov; ribosomal protein S9 [KO:K02997] 324 0.0 K02997  


    Pathway: Calcium signaling pathway ( 65, 33, 26.2%, 126 )
    Query Def Hit ID Hit Def Bit Score E-Value Kegg Ortholog Other Pathways
    APL_all_052305.15293.C1 dre:492486 zgc:103685 [KO:K04137] 178 1.93E-43 K04137
  • Neuroactive ligand-receptor interaction
    • CNSN01-F-002020-501 ptr:451980 ERBB3, LOC451980; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 [EC:2.7.10.1] [KO:K05084] 36 0.265585 K05084  
    CNSN01-F-061923-501 dre:571980 LOC571980; similar to beta2-adrenergic receptor [KO:K04142] 72 1.77456E-11 K04142
  • Neuroactive ligand-receptor interaction
    • APL_all_052305.144.C1 tcr:506211.160 ADP,ATP carrier protein 1, mitochondrial precursor, putative [KO:K05863] 384 0.0 K05863  
    CNSN01-F-007172-501 gga:427633 LOC427633; similar to dopamine receptor D1A - chicken [KO:K04144] 71 1.32686E-11 K04144
  • Neuroactive ligand-receptor interaction
  • Gap junction
    • PEG003-C-204808-501 rno:84025 Ryr2; ryanodine receptor 2, cardiac [KO:K04962] 47 7.01658E-4 K04962  
    CNSN01-F-140036-501 dme:CG7766-PA CG7766; CG7766 gene product from transcript CG7766-RA [KO:K07190] 51 2.2767E-8 K07190
  • Insulin signaling pathway
    • APL_all_052305.8878.C1 dme:CG8472-PB CG8472; CG8472 gene product from transcript CG8472-RB [KO:K02183] 290 0.0 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.103.C1 dme:CG8472-PB CG8472; CG8472 gene product from transcript CG8472-RB [KO:K02183] 218 0.0 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.103.C4 dme:CG8472-PB CG8472; CG8472 gene product from transcript CG8472-RB [KO:K02183] 53 9.5108E-6 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.11468.C1 mmu:12292 Cacna1s; calcium channel, voltage-dependent, L type, alpha 1S subunit [KO:K04857] 37 0.233994 K04857
  • GnRH signaling pathway
    • CNSN01-F-083690-501 rno:25679 Itpr3; inositol 1,4,5-triphosphate receptor 3 [KO:K04960] 43 0.00585923 K04960
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • Taste transduction
  • GnRH signaling pathway
    • APL_all_052305.1017.C2 rno:24807 Tacr1; tachykinin receptor 1 [KO:K04222] 37 0.299947 K04222
  • Neuroactive ligand-receptor interaction
    • APL_all_052305.1.C452 rno:29595 Htr2a; 5-hydroxytryptamine (serotonin) receptor 2A [KO:K04157] 37 0.419901 K04157
  • Neuroactive ligand-receptor interaction
  • Gap junction
    • APL_all_052305.14064.C2 hsa:3709 ITPR2; inositol 1,4,5-triphosphate receptor, type 2 [KO:K04959] 64 2.20483E-9 K04959
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • CNSN01-F-029777-501 dme:CG10079-PB CG10079; CG10079 gene product from transcript CG10079-RB [EC:2.7.10.1] [KO:K04361] 58 2.81212E-7 K04361
  • Cytokine-cytokine receptor interaction
  • Dorso-ventral axis formation
  • Focal adhesion
  • Adherens junction
  • Gap junction
  • Regulation of actin cytoskeleton
  • GnRH signaling pathway
  • Epithelial cell signaling in Helicobacter pylori infection
    • CNSN01-F-064946-501 bta:317697 ITPR1; inositol 1,4,5-triphosphate receptor, type 1 [KO:K04958] 62 9.69425E-9 K04958
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • APL_all_052305.7048.C2 cel:C18E9.1 cal-2; Hypothetical protein C18E9.1 [KO:K02183] 36 0.801024 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.2701.C1 hsa:5332 PLCB4; phospholipase C, beta 4 [EC:3.1.4.11] [KO:K05858] 420 0.0 K05858
  • Inositol phosphate metabolism
  • Phosphatidylinositol signaling system
  • Wnt signaling pathway
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • PEG003-C-228484-501 hsa:7273 TTN, CMD1G; titin [EC:2.7.11.18] [KO:K00907] 149 1.29452E-34 K00907
  • Focal adhesion
  • Regulation of actin cytoskeleton
    • APL_all_052305.14811.C1 ath:At2g41090 T3K9.14; calmodulin-like calcium-binding protein, 22 kDa (CaBP-22) [KO:K02183] 51 1.61613E-5 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • CNSN01-C-003872-501 rno:25400 Camk2a; calcium/calmodulin-dependent protein kinase II, alpha [EC:2.7.11.17] [KO:K04515] 117 9.38026E-25 K04515
  • Wnt signaling pathway
  • Long-term potentiation
  • Olfactory transduction
  • GnRH signaling pathway
    • MCCN20-F-130169-501 rno:25262 Itpr1; inositol 1,4,5-triphosphate receptor 1 [KO:K04958] 98 1.97487E-19 K04958
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • APL_all_052305.10253.C1 tcr:506391.10 calmodulin [KO:K02183] 127 3.34781E-28 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.257.C1 gga:395498 VDAC2; voltage-dependent anion channel 2 [KO:K05862] 426 0.0 K05862  
    APL_all_052305.602.C5 rno:288057 Mylk_predicted; myosin, light polypeptide kinase (predicted) [EC:2.7.11.18] [KO:K00907] 65 2.71296E-9 K00907
  • Focal adhesion
  • Regulation of actin cytoskeleton
    • APL_all_052305.3889.C11 bta:317697 ITPR1; inositol 1,4,5-triphosphate receptor, type 1 [KO:K04958] 279 0.0 K04958
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • APL_all_052305.1729.C1 ddi:DDB0214955 calA; calmodulin [KO:K02183] 130 3.00939E-29 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.12224.C2 mmu:13867 Erbb3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [EC:2.7.10.1] [KO:K05084] 84 9.6793E-16 K05084  
    PEG002-C-010276-301 mmu:13867 Erbb3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [EC:2.7.10.1] [KO:K05084] 112 1.23688E-24 K05084  
    APL_all_052305.1729.C4 ddi:DDB0214955 calA; calmodulin [KO:K02183] 132 1.52606E-29 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • CNSN01-C-002240-501 cel:C18E9.1 cal-2; Hypothetical protein C18E9.1 [KO:K02183] 85 2.77906E-15 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • CNSN01-C-006923-501 rno:24408 Grin1; glutamate receptor, ionotropic, N-methyl D-aspartate 1 [KO:K05208] 127 6.29668E-28 K05208
  • Neuroactive ligand-receptor interaction
  • Long-term potentiation
    • APL_all_052305.103.C8 dme:CG8472-PB CG8472; CG8472 gene product from transcript CG8472-RB [KO:K02183] 296 0.0 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.7987.C1 rno:25262 Itpr1; inositol 1,4,5-triphosphate receptor 1 [KO:K04958] 75 2.3548E-12 K04958
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • CNSN01-F-062370-501 rno:24173 Adra1b; adrenergic receptor, alpha 1b [KO:K04136] 112 1.05335E-23 K04136
  • Neuroactive ligand-receptor interaction
    • APL_all_052305.15648.C1 hsa:51196 PLCE1; phospholipase C, epsilon 1 [KO:K05860] 51 1.92713E-5 K05860
  • Inositol phosphate metabolism
  • Phosphatidylinositol signaling system
    • APL_all_052305.7048.C1 cel:C18E9.1 cal-2; Hypothetical protein C18E9.1 [KO:K02183] 37 0.355095 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.10472.C1 rno:29659 P2rx4; purinergic receptor P2X, ligand-gated ion channel 4 [KO:K05218] 284 0.0 K05218
  • Neuroactive ligand-receptor interaction
    • APL_all_052305.11030.C1 rno:81645 Chrm2; cholinergic receptor, muscarinic 2 [KO:K04130] 39 0.105622 K04130
  • Neuroactive ligand-receptor interaction
  • Regulation of actin cytoskeleton
    • APL_all_052305.1937.C1 dre:378478 egfr; epidermal growth factor receptor [EC:2.7.10.1] [KO:K04361] 51 2.84334E-5 K04361
  • Cytokine-cytokine receptor interaction
  • Dorso-ventral axis formation
  • Focal adhesion
  • Adherens junction
  • Gap junction
  • Regulation of actin cytoskeleton
  • GnRH signaling pathway
  • Epithelial cell signaling in Helicobacter pylori infection
    • APL_all_052305.10794.C1 rno:81636 Adcy2; adenylate cyclase 2 [EC:4.6.1.1] [KO:K08042] 55 3.87001E-6 K08042
  • Purine metabolism
  • Gap junction
  • GnRH signaling pathway
    • APL_all_052305.1017.C3 rno:24807 Tacr1; tachykinin receptor 1 [KO:K04222] 37 0.452833 K04222
  • Neuroactive ligand-receptor interaction
    • APL_all_052305.8878.C2 dme:CG8472-PB CG8472; CG8472 gene product from transcript CG8472-RB [KO:K02183] 284 0.0 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.4038.C5 dme:CG18069-PA CG18069; CG18069 gene product from transcript CG18069-RA CG18069 gene product from transcript CG18069-RC [EC:2.7.11.17] [KO:K04515] 276 0.0 K04515
  • Wnt signaling pathway
  • Long-term potentiation
  • Olfactory transduction
  • GnRH signaling pathway
    • APL_all_052305.144.C2 tcr:506211.160 ADP,ATP carrier protein 1, mitochondrial precursor, putative [KO:K05863] 41 0.0228346 K05863  
    APL_all_052305.4038.C1 dme:CG18069-PA CG18069; CG18069 gene product from transcript CG18069-RA CG18069 gene product from transcript CG18069-RC [EC:2.7.11.17] [KO:K04515] 687 0.0 K04515
  • Wnt signaling pathway
  • Long-term potentiation
  • Olfactory transduction
  • GnRH signaling pathway
    • APL_all_052305.1864.C1 bta:338037 MYLK; myosin, light polypeptide kinase [EC:2.7.11.18] [KO:K00907] 114 5.31385E-24 K00907
  • Focal adhesion
  • Regulation of actin cytoskeleton
    • APL_all_052305.3889.C5 rno:25262 Itpr1; inositol 1,4,5-triphosphate receptor 1 [KO:K04958] 365 0.0 K04958
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • APL_all_052305.1.CB73 xla:380388 kin-1-prov; protein kinase, cAMP-dependent, catalytic, beta [EC:2.7.11.11] [KO:K04345] 606 0.0 K04345
  • Apoptosis
  • Wnt signaling pathway
  • Hedgehog signaling pathway
  • Gap junction
  • Long-term potentiation
  • Olfactory transduction
  • Taste transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
    • APL_all_052305.2635.C1 hsa:5332 PLCB4; phospholipase C, beta 4 [EC:3.1.4.11] [KO:K05858] 598 0.0 K05858
  • Inositol phosphate metabolism
  • Phosphatidylinositol signaling system
  • Wnt signaling pathway
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • CNSN01-F-147797-501 hsa:6543 SLC8A2; solute carrier family 8 (sodium-calcium exchanger), member 2 [KO:K05849] 176 7.52E-43 K05849  
    CNSN01-F-137795-501 gga:427580 LOC427580; similar to histamine H1 receptor - bovine [KO:K04149] 66 6.45373E-10 K04149
  • Neuroactive ligand-receptor interaction
    • PEG002-C-104228-501 ptr:470746 LOC470746; similar to histamine H1 receptor [KO:K04149] 56 5.35294E-11 K04149
  • Neuroactive ligand-receptor interaction
    • CNSN01-F-092353-501 mmu:12287 Cacna1b; calcium channel, voltage-dependent, N type, alpha 1B subunit [KO:K04849] 37 0.68469 K04849
  • Taste transduction
  • Type II diabetes mellitus
    • APL_all_052305.9178.C3 tpv:TP02_0717 calmodulin [KO:K02183] 124 8.59303E-27 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.5977.C1 rno:56827 Cacna1i; calcium channel, voltage-dependent, alpha 1I subunit [KO:K04856] 38 0.198249 K04856  
    MCC015-F-018880-501 hsa:5256 PHKA2; phosphorylase kinase, alpha 2 (liver) [KO:K07190] 109 5.81316E-37 K07190
  • Insulin signaling pathway
    • PEG003-C-032904-501 dme:CG8472-PB CG8472; CG8472 gene product from transcript CG8472-RB [KO:K02183] 103 6.69723E-21 K02183
  • Phosphatidylinositol signaling system
  • Long-term potentiation
  • Olfactory transduction
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • CNSN01-F-050504-501 hsa:4638 MYLK; myosin, light polypeptide kinase [EC:2.7.11.18] [KO:K00907] 251 0.0 K00907
  • Focal adhesion
  • Regulation of actin cytoskeleton
    • APL_all_052305.2933.C3 hsa:492 ATP2B3; ATPase, Ca++ transporting, plasma membrane 3 [EC:3.6.3.8] [KO:K05850] 385 0.0 K05850  
    APL_all_052305.12224.C1 ssc:397070 EGFR; epidermal growth factor receptor [EC:2.7.10.1] [KO:K04361] 90 3.48592E-32 K04361
  • Cytokine-cytokine receptor interaction
  • Dorso-ventral axis formation
  • Focal adhesion
  • Adherens junction
  • Gap junction
  • Regulation of actin cytoskeleton
  • GnRH signaling pathway
  • Epithelial cell signaling in Helicobacter pylori infection
    • APL_all_052305.11175.C2 dre:563111 LOC563111; similar to cysteinyl leukotriene receptor 2 [KO:K04323] 41 0.0177081 K04323
  • Neuroactive ligand-receptor interaction
    • CNSN01-F-045963-501 hsa:3708 ITPR1; inositol 1,4,5-triphosphate receptor, type 1 [KO:K04958] 135 7.53788E-31 K04958
  • Phosphatidylinositol signaling system
  • Gap junction
  • Long-term potentiation
  • Long-term depression
  • GnRH signaling pathway
    • APL_all_052305.365.C1 dre:560392 LOC560392; similar to Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R) [KO:K04194] 78 1.75059E-13 K04194
  • Neuroactive ligand-receptor interaction


    • Pathway: Focal adhesion ( 62, 34, 27.4%, 124 )
    Query Def Hit ID Hit Def Bit Score E-Value Kegg Ortholog Other Pathways
    PEG003-C-219559-501 rno:311391 Cep152_predicted, LOC311391; centrosomal protein 152 (predicted) [KO:K06279] 37 4.67687E-4 K06279
  • Insulin signaling pathway
    • PEG001-C-003547-301 mmu:22371 Vwf; Von Willebrand factor homolog [KO:K03900] 38 0.136982 K03900
  • ECM-receptor interaction
  • Complement and coagulation cascades
    • APL_all_052305.3302.C1 dre:369191 tnr; tenascin R (restrictin, janusin) [KO:K06252] 194 0.0 K06252
  • ECM-receptor interaction
    • PEG001-C-003647-501 mmu:22371 Vwf; Von Willebrand factor homolog [KO:K03900] 38 0.140841 K03900
  • ECM-receptor interaction
  • Complement and coagulation cascades
    • APL_all_052305.11713.C1 mmu:21828 Thbs4; thrombospondin 4 [KO:K04659] 36 0.353743 K04659
  • TGF-beta signaling pathway
  • ECM-receptor interaction
    • CNSN01-F-061863-501 hsa:2932 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.1] [KO:K03083] 112 5.52902E-27 K03083
  • Wnt signaling pathway
  • Hedgehog signaling pathway
  • Axon guidance
  • B cell receptor signaling pathway
  • Insulin signaling pathway
  • Alzheimer's disease
    • MCCN25-F-013887-501 dre:369191 tnr; tenascin R (restrictin, janusin) [KO:K06252] 186 0.0 K06252
  • ECM-receptor interaction
    • APL_all_052305.10450.C1 hsa:7450 VWF, F8VWF; von Willebrand factor [KO:K03900] 200 0.0 K03900
  • ECM-receptor interaction
  • Complement and coagulation cascades
    • APL_all_052305.2633.C1 mmu:170758 Rac3; RAS-related C3 botulinum substrate 3 [KO:K07861] 348 0.0 K07861
  • Wnt signaling pathway
  • Axon guidance
  • VEGF signaling pathway
  • Adherens junction
  • B cell receptor signaling pathway
  • Fc epsilon RI signaling pathway
  • Regulation of actin cytoskeleton
    • CNSN01-F-050504-501 hsa:4638 MYLK; myosin, light polypeptide kinase [EC:2.7.11.18] [KO:K00907] 251 0.0 K00907
  • Calcium signaling pathway
  • Regulation of actin cytoskeleton
    • APL_all_052305.7756.C1 rno:84027 Gsk3b; glycogen synthase kinase 3 beta [EC:2.7.11.1] [KO:K03083] 414 0.0 K03083
  • Wnt signaling pathway
  • Hedgehog signaling pathway
  • Axon guidance
  • B cell receptor signaling pathway
  • Insulin signaling pathway
  • Alzheimer's disease
    • APL_all_052305.9202.C1 mmu:12814 Col11a1; procollagen, type XI, alpha 1 [KO:K06236] 44 0.00319152 K06236
  • ECM-receptor interaction
    • PEG002-C-101325-501 rno:85384 Sos2; son of sevenless homolog 2 (Drosophila) [KO:K03099] 38 0.101159 K03099
  • Dorso-ventral axis formation
  • Gap junction
  • Jak-STAT signaling pathway
  • T cell receptor signaling pathway
  • Fc epsilon RI signaling pathway
  • Regulation of actin cytoskeleton
  • Insulin signaling pathway
  • GnRH signaling pathway
    • PEG003-C-220711-501 mmu:11796 Birc3; baculoviral IAP repeat-containing 3 [KO:K04725] 57 8.15575E-7 K04725
  • Apoptosis
    • APL_all_052305.17672.C1 gga:422316 LOC422316; similar to receptor tyrosine kinase flk-1/VEGFR-2 [EC:2.7.10.1] [KO:K05096] 196 0.0 K05096
  • Cytokine-cytokine receptor interaction
    • APL_all_052305.14629.C1 rno:311391 Cep152_predicted, LOC311391; centrosomal protein 152 (predicted) [KO:K06279] 49 3.39062E-5 K06279
  • Insulin signaling pathway
    • PEG003-C-204948-501 cel:C14F5.5 sem-5; Sex muscle abnormal protein 5 [KO:K04364] 192 0.0 K04364
  • Dorso-ventral axis formation
  • Gap junction
  • Jak-STAT signaling pathway
  • T cell receptor signaling pathway
  • Fc epsilon RI signaling pathway
  • Insulin signaling pathway
  • GnRH signaling pathway
  • Huntington's disease
    • APL_all_052305.18428.C1 dre:394038 zgc:63475 [KO:K06248] 39 0.0967588 K06248
  • ECM-receptor interaction
    • CNSN01-F-058313-501 dre:286832 lamc1; laminin, gamma 1 [KO:K05635] 50 1.77872E-5 K05635
  • ECM-receptor interaction
  • Prion disease
    • CNSN01-F-029777-501 dme:CG10079-PB CG10079; CG10079 gene product from transcript CG10079-RB [EC:2.7.10.1] [KO:K04361] 58 2.81212E-7 K04361
  • Calcium signaling pathway
  • Cytokine-cytokine receptor interaction
  • Dorso-ventral axis formation
  • Adherens junction
  • Gap junction
  • Regulation of actin cytoskeleton
  • GnRH signaling pathway
  • Epithelial cell signaling in Helicobacter pylori infection
    • APL_all_052305.602.C5 rno:288057 Mylk_predicted; myosin, light polypeptide kinase (predicted) [EC:2.7.11.18] [KO:K00907] 65 2.71296E-9 K00907
  • Calcium signaling pathway
  • Regulation of actin cytoskeleton
    • APL_all_052305.5336.C1 xtr:493557 rap1a, MGC89515; rap1a protein [KO:K07836] 296 0.0 K07836
  • Leukocyte transendothelial migration
  • Long-term potentiation
    • APL_all_052305.54.C1 cel:T04C12.5 act-2; Hypothetical protein T04C12.5 [KO:K05692] 751 0.0 K05692
  • Adherens junction
  • Tight junction
  • Leukocyte transendothelial migration
  • Regulation of actin cytoskeleton
    • APL_all_052305.17563.C1 xtr:394698 actc, MGC75679; actin, alpha, cardiac muscle [KO:K05692] 337 0.0 K05692
  • Adherens junction
  • Tight junction
  • Leukocyte transendothelial migration
  • Regulation of actin cytoskeleton
    • APL_all_052305.12224.C1 ssc:397070 EGFR; epidermal growth factor receptor [EC:2.7.10.1] [KO:K04361] 90 3.48592E-32 K04361
  • Calcium signaling pathway
  • Cytokine-cytokine receptor interaction
  • Dorso-ventral axis formation
  • Adherens junction
  • Gap junction
  • Regulation of actin cytoskeleton
  • GnRH signaling pathway
  • Epithelial cell signaling in Helicobacter pylori infection
    • CNSN01-F-106302-501 dme:CG8293-PA CG8293; CG8293 gene product from transcript CG8293-RA CG8293 gene product from transcript CG8293-RB [KO:K04725] 53 6.35276E-6 K04725
  • Apoptosis
    • PEG003-C-221655-501 hsa:7410 VAV2; vav 2 oncogene [KO:K05730] 38 0.508819 K05730
  • T cell receptor signaling pathway
  • B cell receptor signaling pathway
  • Fc epsilon RI signaling pathway
  • Leukocyte transendothelial migration
  • Regulation of actin cytoskeleton
    • PEG003-C-228484-501 hsa:7273 TTN, CMD1G; titin [EC:2.7.11.18] [KO:K00907] 149 1.29452E-34 K00907
  • Calcium signaling pathway
  • Regulation of actin cytoskeleton
    • APL_all_052305.129.C6 hsa:1290 COL5A2; collagen, type V, alpha 2 [KO:K06236] 104 3.7033E-21 K06236
  • ECM-receptor interaction
    • APL_all_052305.16083.C1 rno:315981 RGD1564060_predicted, LOC315981; similar to procollagen, type VI, alpha 3 isoform 4 (predicted) [KO:K06238] 85 1.05979E-22 K06238
  • ECM-receptor interaction
    • APL_all_052305.2691.C4 rno:29433 Pak3; p21 (CDKN1A)-activated kinase 3 [EC:2.7.11.-] [KO:K05733] 516 0.0 K05733
  • Axon guidance
  • T cell receptor signaling pathway
  • Regulation of actin cytoskeleton
    • CNSN01-F-085717-501 cel:F01G12.5a let-2; Lethal protein 2, isoform a [KO:K06237] 39 0.0998429 K06237
  • ECM-receptor interaction
    • PEG003-C-218407-501 hsa:1281 COL3A1; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) [KO:K06236] 37 0.647768 K06236
  • ECM-rece